Pernille Kjærgaard Qwist is an industrial PhD student from the University of Copenhagen, working at Danish pharmaceutical company LEO Pharma.
Pernille has set out to investigate how more PAT (Process Analytical Technology) can be applied to improve process control in manufacture of topical pharma products (creams, ointments, gels, …).
The first phase of her work has been published in the European Journal of Pharmaceutical Sciences.
The article concludes:
“The […] model was used on-line during manufacturing of a gel and manufacturing changes related to dilution of the product were clearly reflected in the batch evolution profiles. The measurements with the PDA reflected the shear rate and frequency ranges relevant for manufacturing and thereby complemented the rheology measurements obtained with a standard rheometer with real time data” [“PDA” is the term used in the article to describe RheoStream VE]. And: “The PDA measures remarkably faster than a standard rheometer and performs the measurements automatically in an on-line mode.”

A preview of the article is available here.

By using the website you agree to the use of cookies more information

The cookie settings on this site are enabled to give you the best experience. If you continue to use the website without changing your cookie settings or clicking Accept, this is considered your acceptance

Close